| Group | Club/Team Name | Team ID | Head Coach |
| A1 | United FC United FC 09B Select |
01032-0011B6U-3496 | Cesar Flores |
| A2 | Spartanburg United Soccer Academy - 01 Spartanburg United 2009B Elite |
01008-001CLB6U-0012 | Loro Lokuji |
| A3 | Carolina FC - 01 Carolina FC 2009 Boys Blue |
01016-001CLB6U-0202 | Fredrick Parlow |
| A4 | CESA Competitive CESA 09B Select Black |
01001-0011B6U-0010 | Matthew Ponto |
| A5 | CESA Competitive CESA Pachuca 09B Select |
01001-0011B6U-1537 | Carlos Buitrago Millan |
| A6 | Greenville Metro FC GMFC-U16 RED |
01038-001CLB6U-0050 | Oker Hernandez Azofeifa |
| B1 | Charlotte Soccer Academy 09 CSA York King |
02030-001CLB6U-0056 | Efrain Tirado |
| B2 | Congaree Rapid FC - 01 CRFC B09 Sky |
02035-0011B6U-0174 | Alexander Peachey |
| B3 | Charlotte Independence Soccer Club 09 CISC Boys YC Blue |
02014-001CLB6U-0692 | Julio Robles |
| B4 | South Carolina United FC - Competitive SCUFC 09 Boys Challenge Red |
02208-208CLB6U-0063 | Jason Vokral |
| B5 | Sumter Soccer Club SSC Thunderbolts B16U 09 |
02015-001CB6U-0167 | Bryan Tash |
| C1 | Beach United FC - 01 Beach United FC Mundial |
03022-0011B6U-1281 | Sonja McGonigal |
| C2 | Daniel Island SA DISA U16B White |
03030-0011B6U-0011 | Austin Higginbotham |
| C3 | Charleston City FC CCFC 2009 Boys |
03014-001IB6U-0052 | Jessie Stament |
| C4 | Florence Soccer Association - 01 FSA 2009 Boys Blue |
03043-0011B6U-0008 | Jonathan Ladron |
| C5 | Charleston Soccer Club LLC CSC 09 Boys Yellow |
03034-001CLB6U-0022 | Brian Purvis |
| C6 | South Carolina Surf Soccer Club SC Surf 09 Blue |
03008-001CLB6U-5694 | Nathaniel Harris |
| C7 | Daniel Island SA DISA U16 Green |
03030-0011B6U-0009 | Sukil Yom |
| D1 | Tormenta FC Academy - 01 TFC 09B Ibis |
03035-001CB6U-0004 | William Cheshire |
| D2 | GSC-Levante UD 2009 Boys | 03012-001CLB6U-2040 | n/a |
| D3 | Kickoff Soccer Academy - 01 KOSA 2009 Boys CBDF |
03033-001CLB6U-1238 | Imer Hernandez |
| D4 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2009 Boys Black |
03040-001PB6U-0003 | Adam Rivera |
| D5 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2009 Boys Gray |
03040-001C2B6U-0006 | Randall Lupton |